Please use this identifier to cite or link to this item: http://theses.ncl.ac.uk/jspui/handle/10443/688
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dc.contributor.authorAspinall, Sebastian Rupert-
dc.date.accessioned2010-03-31T13:53:52Z-
dc.date.available2010-03-31T13:53:52Z-
dc.date.issued2003-
dc.identifier.urihttp://hdl.handle.net/10443/688-
dc.descriptionMD Thesisen_US
dc.description.abstractIn this study, serum and tumour samples were collected from women with primary operable breast cancer and controls. Serum samples were used to measure androgen levels (dehydroepiandrostenseu lphate,a ndrostenedionea nd testosteronele vels) using conventionaEl LI SA techniques.A s "crosstaW' occursb etweens teroid hormonea nd growth factor pathways in breast (and prostate) cancer, it was proposed to measure cerbB-2 levels using a lectin ELISA format. This technique was chosen as a lectin ELISA for cerbB-2 had previously been developed in our laboratory, which showed encouraging results as a diagnostic test for breast cancer.en_US
dc.description.sponsorshipNewcastle Hospitals Special Trustees: Dr Ian Brotherick:en_US
dc.language.isoenen_US
dc.publisherNewcastle Universityen_US
dc.titleThe role of androgens in breast cancer and a letin ELISA for cerbB-2/HER-2en_US
dc.typeThesisen_US
Appears in Collections:School of Surgical and Reproductive Sciences

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